Diphenhydramine Micro Pellets MUPS
Diphenhydramine hydrochlorideÂ is a first-generationÂ antihistamineÂ mainly used to treatÂ allergies. Like most other first-generation antihistamines, the drug also has a powerfulÂ hypnoticÂ effect, and for this reason is often used as a nonprescription sleep aid and a mildÂ anxiolytic. The drug also acts as anantiemetic.
It is produced and marketed under the trade nameÂ BenadrylÂ byÂ McNeil-PPCÂ in the U.S., Canada and South Africa (other trade names in other countries: Dimedrol, Daedalon). It is also found in the name-brand productsÂ Nytol,Â Unisom,Tylenol PM,Â Midol PMÂ andÂ Advil PM, though some Unisom products containÂ doxylamineinstead.
It is available as anÂ over-the-counterÂ (OTC) or prescribed HCl injectable. It may also be used for the treatment ofÂ extrapyramidalÂ side-effects of manyÂ antipsychotics, such as the tremors thatÂ haloperidolÂ can cause.
In addition, injectable diphenhydramine can be used for life-threatening reactions (anaphylaxis) to allergens such as bee stings, peanuts, or latex, rather than risking the side-effects ofÂ epinephrine. It is a member of theÂ ethanolamineÂ class ofantihistaminergicÂ agents. An alternative IUPAC name is [2-(diphenylmethoxy)ethyl]dimethylamine.
Diphenhydramine was one of the first known antihistamines, invented in 1943 by Dr.Â George Rieveschl, a former professor at theÂ University of Cincinnati.Â In 1946, it became the first prescription antihistamine approved by theÂ U.S. Food and Drug AdministrationÂ (FDA).
Diphenhydramine Micro Pellets - Multiple Unit Particle System (MUPS)
Diphenhydramine Micro Granules - Multiple Unit Particle System (MUPS)