Spironolactone Micro Pellets MUPS
pironolactone (marketed under the trade names Aldactone, Novo-Spiroton, Aldactazide,Spiractin, Spirotone, Verospiron or Berlactone) is a diuretic and is used as an antiandrogen.
It is a synthetic 17-lactone drug that is a renal competitive aldosterone antagonist in a class ofpharmaceuticals called potassium-sparing diuretics, used primarily to treat heart failure, ascitesin patients with liver disease, low-renin hypertension, hypokalemia, secondary hyperaldosteronism (such as occurs with hepatic cirrhosis), and Conn's syndrome (primary hyperaldosteronism).
On its own, spironolactone is only a weak diuretic because its effects target the distal nephron (collecting tubule), where urine volume can only be slightly modified; but it can be combined with other diuretics to increase efficacy.
About one person in one hundred with hypertension has elevated levels of aldosterone; in these persons, the antihypertensive effect of spironolactone may exceed that of complex combined regimens of other antihypertensives.
Due to its antiandrogen effect, it can also be used to treat hirsutism. It is also used for treatinghair loss and acne in women, and can be used as a topical medication for treatment of malebaldness.
It is commonly used to treat symptoms of polycystic ovary syndrome (PCOS) such as excess facial hair and acne. It can also be used as part of sex reassignment therapy by trans women.
Spironolactone can cause gynecomastia in males and, unless regularly monitored, should not be given with potassium supplementation for fear of development of hyperkalemia.
Spironolactone Micro Pellets - Multiple Unit Particle System (MUPS)
Spironolactone Micro Granules - Multiple Unit Particle System (MUPS)